Clinical Trial: Antibiotic Therapy of Acute Uncomplicated Colonic Diverticulitis

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: Is Antibiotic Therapy Mandatory for Treatment of Uncomplicated Acute Colonic Diverticulitis: a Randomized Clinical Trial

Brief Summary:

The purpose of this study is to evaluate if antibiotic therapy is necessary for treatment of uncomplicated colonic diverticulitis.

The hypothesis is that Patients with acute uncomplicated colonic diverticulitis will recover the condition without antibiotic therapy and the lack of antibiotic therapy will not lead to complications.

The patients will be randomized to conservative treatment with and without antibiotic therapy.

Detailed Summary:
Sponsor: Uppsala University

Current Primary Outcome: discharge without complications +/- antibiotic therapy [ Time Frame: Within 30 days after discharge ]

Original Primary Outcome: Same as current

Current Secondary Outcome: to evaluate length of hospital stay, cost and late complications [ Time Frame: one year after admission ]

Original Secondary Outcome: Same as current

Information By: Uppsala University

Dates:
Date Received: November 4, 2009
Date Started: November 2002
Date Completion:
Last Updated: December 22, 2011
Last Verified: December 2011