Clinical Trial: Scandinavian Diverticulitis Trial

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: Scandinavian Diverticulitis Trial. Laparoscopic Lavage vs Primary Resection as Treatment for Perforated Diverticulitis. A Randomized Prospecti

Brief Summary: The purpose of this study is to determine whether laparoscopic lavage changes the rate of severe complications in patients with acute perforated diverticulitis who traditionally are treated with primary resection.

Detailed Summary: Acute diverticulitis is a common disease in the western world. Perforation of the acute diverticulitis with peritonitis is a feared complication and standard treatment (primary sigmoid resection such as Hartmann`s procedure) still has unsatisfactory results. Both mortality and morbidity are quite high. Several uncontrolled trials have reported a lower mortality and morbidity when acute perforated diverticulitis is treated with laparoscopic lavage instead of radical surgery. The investigators wish to conduct a randomized multicenter trial in Scandinavia in order to compare the rates of severe postoperative complications in acute perforated diverticulitis if treated by traditional primary sigmoid resection or by laparoscopic lavage. The investigators are planning to include all patients admitted to the participating hospitals with clinical and radiological findings of acute perforated diverticulitis.
Sponsor: University Hospital, Akershus

Current Primary Outcome: 90 days complication rate [ Time Frame: 90 days ]

Original Primary Outcome: Same as current

Current Secondary Outcome: Quality of life [ Time Frame: 1 year ]

Original Secondary Outcome: Same as current

Information By: University Hospital, Akershus

Dates:
Date Received: January 12, 2010
Date Started: January 2010
Date Completion:
Last Updated: January 23, 2017
Last Verified: January 2017