Clinical Trial: Fingerprinting of Impulsivity

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Observational

Official Title: Fingerprinting of Impulsivity in Four Diagnostic and Statistical Manual of Mental Disorders, Version 5 (DSM-5) Psychiatric Disorders That Have Been Clinically Associated With Impulsivity Using a Batte

Brief Summary: The study aims to examine a battery of behavioral and questionnaire measures in 4 disorders clinically associated with impulsivity and in health controls, to: 1) investigate if the different populations have a distinct behavioral profile, and 2) to investigate if there are specific measures that are reliable and sensitive measures of impulsivity across diagnoses.

Detailed Summary:
Sponsor: Boehringer Ingelheim

Current Primary Outcome:

  • Stability in scores measured as change from baseline to follow-up visit at 4 (+/-1) weeks for Go/No Go Task [ Time Frame: up to 5 weeks ]
  • Stability in scores measured as change from baseline to follow-up visit at 4 (+/-1) weeks for Stop Signal Reaction Time (SSRT) Task [ Time Frame: up to 5 weeks ]
  • Stability in scores measured as change from baseline to follow-up visit at 4 (+/-1) weeks for Computerized Monetary Choice Task [ Time Frame: up to 5 weeks ]
  • Stability in scores measured as change from baseline to follow-up visit at 4 (+/-1) weeks for Barratt Impulsiveness Questionnaire version 11 (BIS-11) [ Time Frame: up to 5 weeks ]
  • Stability in scores measured as change from baseline to follow-up visit at 4 (+/-1) weeks for Immediate Memory Task (IMT) [ Time Frame: up to 5 weeks ]
  • Stability in scores measured as change from baseline to follow-up visit at 4 (+/-1) weeks for Urgency, Premeditation, Perseverance, Sensation Seeking and Positive Urgency (UPPs-P) Impulsive Behavior Scale [ Time Frame: up to 5 weeks ]


Original Primary Outcome:

  • Stability in scores measured as change from baseline to follow-up visit at 4 (+/-1) weeks for Go/No Go Task [ Time Frame: up to 5 weeks ]
  • Stability in scores measured as change from baseline to follow-up visit at 4 (+/-1) weeks for Stop Signal Reaction Time (SSRT) Task [ Time Frame: up to 5 weeks ]
  • Stability in scores measured as change from baseline to follow-up visit at 4 (+/-1) weeks for Computerized Monetary Choice Task [ Time Frame: up to 5 weeks ]
  • Stability in scores measured as change from baseline to follow-up visit at 4 (+/-1) weeks for Barratt Impulsiveness Questionnaire version 11 (BIS-11) [ Time Frame: up to 5 weeks ]
  • Stability in scores measured as change from baseline to follow-up visit at 4 (+/-1) weeks for Urgency, Premeditation, Perserverance, Sensation Seeking and Positive Urgency (UPPs-P) Impulsive Behavior Scale [ Time Frame: up to 5 weeks ]
  • Stability in scores measured as change from baseline to follow-up visit at 4 (+/-1) weeks for Immediate Memory Task (IMT) [ Time Frame: up to 5 weeks ]


Current Secondary Outcome: Antisaccade performance measured as change from baseline to follow-up visit at 4 (+/-1) weeks on the eye tracker [ Time Frame: up to 5 weeks ]

Original Secondary Outcome: Same as current

Information By: Boehringer Ingelheim

Dates:
Date Received: March 23, 2016
Date Started: July 22, 2016
Date Completion: July 13, 2018
Last Updated: May 15, 2017
Last Verified: May 2017