Clinical Trial: Genome-wide Study for Disease Susceptibility Gene(s) in Patients With Hand Osteoarthritis

Study Status: Completed
Recruit Status: Unknown status
Study Type: Observational

Official Title: Genome-wide Study for Disease Susceptibility Gene(s) in Patients With Hand Osteoarthritis

Brief Summary:

This is a case-control study involving one medical center and one research institute to develop a data-set containing a minimum of 100 osteoarthritis cases, minimum of 100 independent controls of similar gender ratio and a minimum of 100 disease controls (cases with hip and/or knee OA) to associate DNA sequence (allelic) variations in candidate genes with osteoarthritis phenotypes.

This study is intended to begin at the Institute of Biomedical Sciences at Academia Sinica (which includes National Genotyping Center (NGC) and National Clinical Core (NCC)), National Taiwan University Hospital.


Detailed Summary:
Sponsor: National Taiwan University Hospital

Current Primary Outcome: Hand Osteoarthritis related gene expression assay [ Time Frame: 4 years ]

The sample was collected from the patient who suffered from osteoarthritis of finger joints, espcially DIP joint. The operation was perfomed due to arthrodesis procedure. So we set the outcome measurement goal for the arthrodesis successful rate.


Original Primary Outcome: Same as current

Current Secondary Outcome:

Original Secondary Outcome:

Information By: National Taiwan University Hospital

Dates:
Date Received: November 5, 2013
Date Started: February 2012
Date Completion: November 2016
Last Updated: November 5, 2013
Last Verified: November 2013