Clinical Trial: Antimicrobial Susceptibility Testing Guided Antibiotic Selection Strategies in Salvage Helicobacter Pylori Treatment

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Interventional

Official Title: Efficacy of Two Antimicrobial Susceptibility Testing Guided Antibiotic Selection Strategies in Salvage Helicobacter Pylori Treatment

Brief Summary: Helicobacter pylori (H. pylori), which infects about 50% of the global population, has been recognized as a main risk factor of multiple gastric pathologies, especially non-cardiac gastric cancer. Strongly evidence supports that H. pylori eradication is an effective approach to reduce the incidence of those pathologies.

Detailed Summary:
Sponsor: Shandong University

Current Primary Outcome: Eradication rates in 2 groups [ Time Frame: 6 months ]

Original Primary Outcome: Eradication rates in 2 groups [ Time Frame: 5 months ]

Current Secondary Outcome:

  • the rate of improving dyspepsia symptoms after H. pylori eradication [ Time Frame: 6 months ]
  • the rate of adverse events happening [ Time Frame: 6 months ]
  • the rate of good compliance (take pills more than 90%) [ Time Frame: 5 months ]
  • difference of cost per patient for each eradication achieved in 2 groups [ Time Frame: 6 months ]


Original Secondary Outcome:

  • the rate of improving dyspepsia symptoms after H. pylori eradication [ Time Frame: 5 months ]
  • the rate of adverse events happening [ Time Frame: 5 months ]
  • the rate of good compliance (take pills more than 90%) [ Time Frame: 5 months ]
  • difference of cost per patient for each eradication achieved in 2 groups [ Time Frame: 5 months ]


Information By: Shandong University

Dates:
Date Received: December 4, 2016
Date Started: April 20, 2017
Date Completion: September 2017
Last Updated: April 23, 2017
Last Verified: April 2017