Clinical Trial: Epidemiology of Treatment Resistant Depression in Taiwan

Study Status: Completed
Recruit Status: Completed
Study Type: Observational

Official Title: Epidemiology of Treatment Resistant Depression in Taiwan

Brief Summary: The purpose of this study is to assess the epidemiology of Treatment Resistant Depression (TRD) in the nationally insured population in Taiwan including incidence, duration of clinical episodes, and prevalence by age and sex.

Detailed Summary: This is a retrospective study of approximately one million subjects randomly selected from an anonymized database National Health Insurance Research Database (NHIRD). Participants aged 18 years or older who have had neither a depression diagnosis nor a dispensing of an antidepressant medication in the last four months of 2004 will enter the study when they receive in 2005 a depression diagnosis and a dispensing of an antidepressant medication within 30 days of each other and will be followed up to 8 years or until they have 4 months with neither a depression diagnosis nor a dispensing of an antidepressant medication. Treatment Resistant Depression (TRD) Incidence, TRD prevalence by age and sex and duration of clinical episodes will be estimated.
Sponsor: Johnson & Johnson Pte Ltd

Current Primary Outcome:

  • Incidence Percentage of Participants with Treatment Resistant Depression [ Time Frame: Approximately 8 Years ]
    The percentage of beneficiaries of Taiwan's health insurance plan who developed treatment resistant depression during 2005
  • Prevalence Percentage of Participants with Treatment Resistant Depression [ Time Frame: Approximately 8 Years ]
  • Duration of an episode of Depression [ Time Frame: Approximately 8 Years ]
    Time from onset of depression to cessation of depression visits and medications.


Original Primary Outcome:

  • Incidence of Treatment Resistant Depression [ Time Frame: Approximately 8 Years ]
  • Prevalence of Treatment Resistant Depression [ Time Frame: Approximately 8 Years ]
  • Duration of an episode of Depression [ Time Frame: Approximately 8 Years ]


Current Secondary Outcome:

  • Healthcare costs [ Time Frame: Approximately 8 Years ]
    Direct healthcare cost associated with depression treatment will be assessed.
  • Number of Participants With Comorbidities [ Time Frame: Approximately 8 Years ]
  • Medications used by Participants with Treatment Resistant Depression [ Time Frame: Approximately 8 Years ]


Original Secondary Outcome: Same as current

Information By: Johnson & Johnson Pte Ltd

Dates:
Date Received: February 22, 2016
Date Started: September 2015
Date Completion:
Last Updated: March 22, 2016
Last Verified: March 2016