Clinical Trial: The Effects of Light Therapy on Circadian Rhythms, Sleep, and Mood in Postpartum Depression

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: The Effects of Light Therapy on Circadian Rhythms, Sleep, and Mood in Postpartum Depression

Brief Summary: The proposed study aims to establish the feasibility of light therapy for postpartum depression delivered via Re-Timer, demonstrate its preliminary efficacy, and illuminate relationships between circadian shifts and mood changes using a novel, home-based circadian biomarker assessment paradigm (salivary dim light melatonin onset; DLMO).

Detailed Summary:
Sponsor: University of Michigan

Current Primary Outcome:

• Change from Baseline Score of the Hamilton Depression Rating Scale-Seasonal Affective Version (SIGH-SAD) at 5 weeks [ Time Frame: After five weeks of light therapy ]
  Clinician-rated depression symptom severity measure
• Change from Baseline Score of the Edinburgh Postnatal Depression Scale at 5 weeks [ Time Frame: After five weeks of light therapy ]
  Self-report of depression symptoms
• Change from Baseline Time of Dim Light Melatonin Onset at 5 weeks [ Time Frame: After five weeks of light therapy ]
  Onset of melatonin in dim light conditions as measured in saliva

Original Primary Outcome: Same as current

Current Secondary Outcome:

Original Secondary Outcome:

Information By: University of Michigan

Dates:
Date Received: May 10, 2016
Date Started: June 2015
Date Completion:
Last Updated: December 19, 2016
Last Verified: December 2016