Clinical Trial: A Clinical Study to Compare Two Revascularization Protocols to Treat Non-vital Teeth With Incomplete Root Formation
Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Interventional
Official Title: A Randomized Controlled Clinical Trial of Regenerative Protocols to Treat Immature Necrotic Teeth
Brief Summary:
Both methods tested in this study disinfect the non-vital root canals and induce blood clot formation inside the root canal. One method places calcium hydroxide inside the root canal after disinfection and the blood clot is induced four weeks later.
The other method performs disinfection and induction of blood clot in one appointment. The investigators hypothesize that both methods will obtain the same success rate in eliminating infection, increase in root length and canal walls thickness.
Detailed Summary: Collagen is placed on top of the blood clot, followed by white MTA. Glass ionomer is used to seal the access to the canal, which will be replaced by a permanent restoration 3 months later.
Sponsor: University of Michigan
Current Primary Outcome: Absence of infection and inflammation. [ Time Frame: 12 and 24 months after the induction of blood clot ]
Original Primary Outcome: Same as current
Current Secondary Outcome:
- Changes in root length and canal wall width [ Time Frame: Baseline and 12 months after the induction of blood clot ]
- Changes in root length and canal wall width [ Time Frame: Baseline and 24 months after the induction of blood clot ]
Original Secondary Outcome: Same as current
Information By: University of Michigan
Dates:
Date Received: January 7, 2013
Date Started: October 2012
Date Completion: April 2017
Last Updated: November 16, 2016
Last Verified: November 2016
