Clinical Trial: Pulp Revascularization Versus MTA Apexification

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: A Comparative Study Between Pulp Revascularization and MTA Apexification in Necrotic Immature Anterior Teeth, A Randomized Controlled Trial

Brief Summary: This study compared the efficiency of pulp revascularization and MTA apexification in the treatment of patients with necrotic immature anterior teeth.

Detailed Summary: the participants with 66 anterior necrotic immature teeth were randomly assigned into two equal groups with 33 teeth per each, according to regeneration and MTA apexification. At the first visit, all teeth were accessed and irrigated with NaOCl then a TAP was applied as intra-appointment intracanal medication. At the second visit, after removal of the medication with the irrigation, bleeding was initiated into the canal and isolated by the MTA in the orifice in the regeneration group. While in the Apexification group, the MTA was packed apically and all teeth were finally restored with resin composite restorations. The patients were recalled after 1, 3, 6, and 9 months for clinical and radiographic follow up.
Sponsor: Enas Ebrahim Sayed

Current Primary Outcome: Pain intensity measures [ Time Frame: 2 days ]

self reported pain intesity at 4, 12, 24, and 48 hours.(0= no pain and 100=worst pain) with a scale from 0 to 100 after the two visits.


Original Primary Outcome: Same as current

Current Secondary Outcome:

  • Resolution of periapical pathosis [ Time Frame: 9 months ]
    Radiographically: by comparing radiolucencies in 9 months postoperative radiograph to the baseline radiograph.
  • Amount of radiographic increase in root length: [ Time Frame: baseline and 9 months ]
    Root length was measured as a straight line from the cement-enamel junction to the radiographic apex of the tooth in millimeters = (9months follow up length - baseline length)
  • Amount of radiographic increase in the root dentinal wall thickness: [ Time Frame: baseline and 9 months ]
    Dentin thickness was measured by =root thickness-pulp space and compared to the baseline radiograph measurements.
  • Decrease of apical diameter: [ Time Frame: baseline and 9 months ]
    the diameter of the apical foramen was measured in millimeters and compared to the baseline radiograph measurements


Original Secondary Outcome: Same as current

Information By: Cairo University

Dates:
Date Received: March 7, 2017
Date Started: December 6, 2012
Date Completion:
Last Updated: March 19, 2017
Last Verified: March 2017