Clinical Trial: Clinical Assessment of Caries and Dental Plaque Based on Auto-fluorescence Imaging System

Study Status: Enrolling by invitation
Recruit Status: Enrolling by invitation
Study Type: Observational

Official Title: Clinical Detection and Quantification of Caries and Dental Plaque Based on Auto-fluorescence Imaging System: An Observational Study

Brief Summary: The purpose of this study was to evaluate the applicability of auto-fluorescence imaging system to detect and quantify caries and dental plaque. Participants were advised to rinse their mouth with distilled water to exclude any chance of fluorescence from food debris. A well trained physicist majored in optical spectroscopy captured auto-fluorescence images of buccal aspects of two maxillary central incisors and occlusal aspects of four first molars from each patient in a dark room. Then they chewed a disclosing agent to assess the Quigley Hein plaque index modified by Turesky of each tooth. Furthermore, participants were also required to brush their teeth for 3min, then International Caries Detection and Assessment System（ICDAS）codes of relevant teeth to evaluate degrees of caries were recorded by an experienced dentist using a mouth mirror and explorer. The Spearman rank correlation coefficient between colorimetric parameters of fluorescence image and the plaque index and ICDAS code were calculated to evaluate the sensitivity and specificity of auto-fluorescence imaging system.

Detailed Summary:
Sponsor: Hui Chen

Current Primary Outcome:

  • Auto-fluorescence image assessment [ Time Frame: 1 week after image collection ]
    Colorimetric parameters of auto-fluorescence images of buccal aspects of two maxillary central incisors and occlusal aspects of four first molars from each patient were calculated to get the Percentage Plaque Index (PPI). PPI is defined as the ratio between area of dental plaque on teeth and the whole teeth area.
  • The Quigley Hein plaque index modified by Turesky [ Time Frame: right after disclosing ]

    After disclosing dental plaque, plaque index was evaluated as following scoring system:0 no plaque;

    1. separate flecks of plaque at the cervical margin of the margin of the tooth;
    2. a thin continuous band of plaque (up to 1 mm) at the cervical margin;
    3. a band of plaque wider than 1 mm but covering less than (1/3)rd of crown;
    4. plaque covering at least (1/3)rd but less than (2/3)rd of the crown;
    5. plaque covering (2/3)rd or more of the crown
  • ICDAS scoring results [ Time Frame: right after oral detection ]

    After brushing teeth, ICDAS codes were recorded by an experienced dentist using a mouth mirror and explorer:0 sound；

    1. first visual change in enamel;
    2. distinct visual change in enamel;
    3. loc

      Original Primary Outcome: Same as current

      Current Secondary Outcome:

      Original Secondary Outcome:

      Information By: The Dental Hospital of Zhejiang University School of Medicine

      Dates:
      Date Received: January 30, 2017
      Date Started: May 2016
      Date Completion: September 2017
      Last Updated: January 30, 2017
      Last Verified: January 2017