Clinical Trial: A Study to Investigate the Anti-Plaque Effect of AN0128 Toothpaste

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: Clinical Research Study to Investigate the Anti-Plaque Effect of a Prototype Toothpaste Containing an Anacor Material Via the MGMPI Method

Brief Summary: The objective of this study was to evaluate the anti-plaque efficacy of the Anacor prototype dentrifice as compared to commercial control products following a single use of the dentrifice.

Detailed Summary: The widespread successful use of triclosan as an anti-inflammatory and anti-bacterial agent is well documented. The standard dentrifice has demonstrated a robust anti-plaque and anti-inflammatory effect providing multiple benefits. There is a clear value to identify additional agents with the same dual action with a comparable or an enhanced level of efficacy. This study examined the anti-plaque efficacy following a single use of the prototype dentifrice.
Sponsor: Pfizer

Current Primary Outcome: Reduction in the gingival margin plaque index in a 24-hour post-treatment (no brushing) [ Time Frame: Baseline (time zero), 24 hour time point ]

Original Primary Outcome: Same as current

Current Secondary Outcome:

Original Secondary Outcome:

Information By: Pfizer

Dates:
Date Received: September 24, 2008
Date Started: November 2007
Date Completion:
Last Updated: June 22, 2015
Last Verified: September 2008