Clinical Trial: Review of Kidney Biopsies of Dent Disease Patients

Study Status: Completed
Recruit Status: Completed
Study Type: Observational

Official Title: Systematic Review of Clinical Biopsies of Dent Disease Patients

Brief Summary: This study is being done to obtain pathology reports from all patients in the Dent disease registry who have had a kidney biopsy. The investigator will collect the biopsy slides and reports in an attempt to determine if they have any common findings.

Detailed Summary:

If the patient agrees to be in the study, the patient will be asked to participate in the following:

  • Sign a consent form indicating the patient's willingness to participate.
  • Provide a signed medical release form allowing the investigator to request your official kidney biopsy reports, and also allowing the investigator to request the original slides for review. At the end of the study, all slides will be returned to the referring facility.
  • The investigator will also review your medical record

Sponsor: Mayo Clinic

Current Primary Outcome: Biopsy changes [ Time Frame: 2 years ]

The primary outcome will be to determine the number of glomeruli, percent globally sclerotic glomeruli, percent focally sclerotic glomeruli, and the severity of interstitial fibrosis (none, mild, moderate, severe) and interstitial crystals (none, mild, moderate, severe)


Original Primary Outcome: Same as current

Current Secondary Outcome:

Original Secondary Outcome:

Information By: Mayo Clinic

Dates:
Date Received: December 6, 2013
Date Started: October 2013
Date Completion:
Last Updated: September 19, 2015
Last Verified: September 2015