Clinical Trial: Follow up of Nasolacrimal Intubation in Adults
Study Status: Completed
Recruit Status: Completed
Study Type: Observational
Official Title: Long Term Follow up of Nasolacrimal Intubation in Adults With Mild Epiphora
Brief Summary:
For patients with chronic epiphora, Dacryocystorhinostomy is currently the gold standard treatment, with a success rate of 80-90% according to literature. Another available treatment, which is far less used, in nasolacrimal intubation, using a silicone tube.
In our study, we would like to find the efficacy of nasolacrimal duct intubation, which was performed in our medical center on a few hundred patients with mild epiphora.
Study hypothesis: nasolacrimal intubation in adults, with a clinically mild epiphora, is close in it's efficacy to the Dacryocystorhinostomy procedure.
Detailed Summary:
Under normal conditions, the amount of tears excreted from lacrimal glands to the eye is equal to the amount drained through the tear duct. Epiphora in adults usually involves a blockage of the lacrimal sac or the nasolacrimal duct. Epiphora causes tearing in patients, which can be treated sympthomatically in a conservative way (antibiotic treatment, probing of the tear duct, pressure irrigation of the tear duct) or therapeutic in an invasive way. The invasive treatment includes one of the following:
- Dacryocystorhinostomy - surgery for reconstructing an alternative path for tear drainage.
- Nasolacrimal intubation - inserting a silicone tube through the tear duct. The tube is usually removed after 3-6 months.
Currently, there are only a few reports regarding the efficacy of nasolacrimal intubation, all with a small number of research subjects. Also, these reports have stratified the patients according to the location of the tear duct blockage, and didn't take into account the severity of the blockage (ie the severity of symptoms) prior to performing the intubation.
In our research, we would like to find the efficacy of nasolacrimal intubation which was performed in our medical center on a few hundred patients with mild epiphora, and to compare in with the efficacy of the Dacryocystorhinostomy - which is 80-90% according to literature.
Sponsor: Shaare Zedek Medical Center
Current Primary Outcome: Patient being completely free of tearing. [ Time Frame: 1 year. ]
Original Primary Outcome: Same as current
Current Secondary Outcome: Following nasolacrimal intubation, did the patient need a Dacryocystorhinostomy surgery. [ Time Frame: 1 year ]
Original Secondary Outcome: Same as current
Information By: Shaare Zedek Medical Center
Dates:
Date Received: June 26, 2008
Date Started: January 2000
Date Completion:
Last Updated: June 26, 2008
Last Verified: June 2008
