Clinical Trial: Genetic Analysis of Children With Cyclic Vomiting Syndrome (CVS) and Migraines

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Observational

Official Title: Genetic Analysis of Children With Cyclic Vomiting Syndrome and Migraines

Brief Summary: The purpose of this study is to determine if there are genetic variations that can explain a genetic basis for cyclic vomiting syndrome (CVS).

Detailed Summary: The purpose of this study is to determine if there are genetic variations that can explain a genetic basis for cyclic vomiting syndrome (CVS), various phenotypes of CVS (e.g. menstrual, Sato, calendar-tied) and migraine headaches (e.g. with aura, without aura, hemiplegic migraine). This information will allow physicians to improve care for patients who have been diagnosed with this disease and to provide their parents with more complete information regarding the cause of this disease. This research is being done because many unanswered questions remain regarding children with CVS.
Sponsor: Medical College of Wisconsin

Current Primary Outcome: Identify novel genes that contribute to the risk of CVS using genomewide association analysis approach. [ Time Frame: 3 years ]

Original Primary Outcome: Same as current

Current Secondary Outcome: Perform genotype-phenotype correlations between genetic profiles and various phenotypes of CVS (e.g. menstrual, Sato, calendar-tied) and migraine headaches (e.g. with aura, without aura, hemiplegic migraine) [ Time Frame: 3 years ]

Original Secondary Outcome: Same as current

Information By: Medical College of Wisconsin

Dates:
Date Received: July 31, 2008
Date Started: January 2008
Date Completion: December 2019
Last Updated: January 30, 2017
Last Verified: January 2017