Clinical Trial: Measuring Cyclotorsion on Scanning Laser Ophthalmoscopy (SLO)-Fundus Photographs

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Interventional

Official Title: Measuring Cyclotorsion on Scanning Laser Ophthalmoscopy (SLO)-Fundus Photographs Using the Integrated Algorithm by Heidelberg Spectralis

Brief Summary:

Pre-Study: Evaluation of the inter- and intrarater reliability of the integrated algorithm by Heidelberg Spectralis for measuring cyclotorsion on SLO-fundus fotographs, and assessment of the influence of measuring with or without eye tracker.

Study: Comparison of cyclotorsion measurements in patients with forth nerve palsy and in healthy controls on SLO-fundus fotographs using the integrated algorithm by Heidelberg Spectralis


Detailed Summary:
Sponsor: University of Zurich

Current Primary Outcome:

  • pre-study: reliability of repeated measurements of excyclotorsion in degrees on SLO-fundus fotographs [ Time Frame: 3 months ]
    pre-study: inter- and intrarater reliability of the device with or without eye tracker; excyclotorsion in degrees (based on the line crossing the fovea and the center of the optic nerve head) as provided by the integrated algorithm by Heidelberg Spectralis
  • study: excyclotorsion in degrees on SLO-fundus fotographs [ Time Frame: 12 months ]
    study: comparison of cyclotorsion measurements in healthy controls compared to patients with forth nerve palsy; excyclotorsion in degrees (based on the line crossing the fovea and the center of the optic nerve head) as provided by the integrated algorithm by Heidelberg Spectralis


Original Primary Outcome: Same as current

Current Secondary Outcome: study: excyclotorsion in degrees on tangent screen, double maddox and fundus photographs [ Time Frame: 12 months ]

validation of the cyclotorsion measurement with the Heidelberg Spectralis device against tangent screen [degrees], double maddox [degrees] and fundus photographs [degrees]


Original Secondary Outcome: Same as current

Information By: University of Zurich

Dates:
Date Received: December 9, 2015
Date Started: December 2015
Date Completion: August 2017
Last Updated: May 3, 2017
Last Verified: May 2017