Clinical Trial: The Use of Capsaicin Challenge for Diagnosis, Monitoring and Follow-up of Chronic Cough.

Study Status: Completed
Recruit Status: Unknown status
Study Type: Interventional

Official Title: The Use of Capsaicin Challenge for Diagnosis, Monitoring and Follow-up of Chronic Cough.

Brief Summary: The purpose of this study is to determine whether the capsaicin challenge can improve the diagnosis, treatment, monitoring and follow-up in patients with chronic cough.

Detailed Summary: Capsaicin is administrated in incremental concentrations with two inhalations of normal saline solution. Patients are instructed to exhale to functional residual capacity and than to inhale through the mouthpiece for 1 second (single breath inhalation). The number of coughs in the first 10 seconds after each inhalation is counted. C2; the concentration of which the patient responded by 2 coughs, C5;the concentration of which the patient responded by 5 coughs. The challenge ends at C5.
Sponsor: Tel-Aviv Sourasky Medical Center

Current Primary Outcome: cough reflex hypersensitivity [ Time Frame: 3 months ]

Original Primary Outcome: Same as current

Current Secondary Outcome:

Original Secondary Outcome:

Information By: Tel-Aviv Sourasky Medical Center

Dates:
Date Received: March 7, 2013
Date Started: March 2013
Date Completion: December 2013
Last Updated: March 7, 2013
Last Verified: March 2013