Clinical Trial: The Effect of Ebastine/Pseudoephedrine on Subacute Cough

Study Status: Terminated
Recruit Status: Unknown status
Study Type: Interventional

Official Title: The Effect of Ebastine/Pseudoephedrine on Subacute Cough :a Randomized Placebo-controlled Trial

Brief Summary: To determine whether ebastine/pseudoephedrine is effective on subacute cough.

Detailed Summary:

  1. Visit 0 week

    • Patients with subacute cough,area randomized to either ebastine/pseudoephedrine or placebo for 1 week.
    • The cough severity and quality of life were measure with VAS score and cough-specific quality-of-life questionnaire(CQLQ)
  2. Visit 1 week check VAS score and CQLQ
  3. Visit 4 weeks check VAS score and CQLQ

Sponsor: Seoul National University Hospital

Current Primary Outcome: Change of VAS score [ Time Frame: 1 week later after administration of ebastine/pseudoephedrine or placebo ]

Original Primary Outcome: Same as current

Current Secondary Outcome:

  • Change of VAS score [ Time Frame: 4 weeks later after administration of ebastine/pseudoephedrine or placebo ]
  • The proportion of patients with more than 50 percent decrease in VAS score [ Time Frame: 1 week ]
  • Change of CQLQ score [ Time Frame: 1week later after administration of ebastine/pseudoephedrine or placebo ]
  • Change of CQLQ score [ Time Frame: 4 weeks later after administration of ebastine/pseudoephedrine or placebo ]
  • The adverse events [ Time Frame: 4 weeks ]


Original Secondary Outcome: Same as current

Information By: Seoul National University Hospital

Dates:
Date Received: February 16, 2014
Date Started: September 2011
Date Completion:
Last Updated: February 16, 2014
Last Verified: February 2014