Clinical Trial: Coronary Artery Aneurysm Registry

Study Status: Active, not recruiting
Recruit Status: Active, not recruiting
Study Type: Observational [Patient Registry]

Official Title: Coronary Artery Aneurysms: Incidence, Management and Long Term Prognosis

Brief Summary: International registry gathering patients with angiographically confirmed coronary aneurysm.

Detailed Summary:

INTRODUCTION AND RATIONALE:

Coronary artery aneurysm is defined as coronary dilatation which exceeds the diameter of normal adjacent segments or the diameter of the patient's largest coronary vessel by 1.5 times. Described by Bourgon, it is an uncommon disease which has been diagnosed with increasing frequency since the advent of coronary angiography. The incidence varies from 1.5% to 5% with male dominance and a predilection for the right coronary artery.

Although several causes have been reported, atherosclerosis accounts for 50% of coronary aneurysms in adults. Reported complications include thrombosis and distal embolization, rupture and vasospasm, causing ischemia, heart failure or arrhythmias. The natural history and prognosis remains obscure, since definitive data are scarce. Controversies persist regarding the use of medical management (antithrombotic) or interventional/surgical procedures.

OBJECTIVES.

Taking into account the classical coronary aneurysm definition, the investigators propose:

  • ANATOMIC OBJECTIVES.

    • To characterize coronary aneurysms frequency over all cause invasive coronary angiography.
    • To describe anatomy, location and aneurysms features.
    • To assess intracoronary imaging data if available.
    • To describe the natural history, when evolutive chats were available

  • CLINICAL OBJECTIVES.

    • Any cause death [ Time Frame: 12 months ]
      dicotomic variable (yes/no)
    • Cardiology readmission [ Time Frame: 12 months ]
      dicotomic variable (yes/no)


    Original Primary Outcome: Same as current

    Current Secondary Outcome:

    Original Secondary Outcome:

    Information By: St Carlos Hospital, Madrid, Spain

    Dates:
    Date Received: September 26, 2015
    Date Started: September 2015
    Date Completion: December 2016
    Last Updated: October 12, 2016
    Last Verified: October 2016