Clinical Trial: Ocular Surface Disorders in Patients in Intensive Care Units, a Comparative Study of Three Preventive Approaches

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: Ocular Surface Disorders in Patients in Intensive Care Units, a Comparative Study

Brief Summary:

60% of the patients hospitalized in intensive care and sedated suffer from insufficient inferior eyelid occlusion. Thus, they are at risk for corneal damage (estimated risk 20% to 57%). The prevention of such corneal damage can be done using several techniques (artificial tears, eyelid occlusion dressing, aqueous gel). The efficacy of these techniques has never been compared in a rigorous study. Therefore it is not yet possible to determine an evidence-based strategy to prevent corneal damage in intensive care patients.

This study aims at assessing the efficacy of primary prevention of corneal lesions in intensive care patients, in order to elaborate an evidence-based nursing protocol.

Detailed Summary:
Sponsor: Fondation Ophtalmologique Adolphe de Rothschild

Current Primary Outcome: Incidence rate of corneal lesions (grade > 0 in the Mercieca classification) [ Time Frame: participants will be followed for the duration of stay in intensive care unit, an expected average of 1 week ]

Original Primary Outcome: Same as current

Current Secondary Outcome:

Original Secondary Outcome:

Information By: Fondation Ophtalmologique Adolphe de Rothschild

Dates:
Date Received: January 16, 2015
Date Started: December 2014
Date Completion:
Last Updated: February 10, 2017
Last Verified: February 2017