Clinical Trial: Effect of Intravitreal Bevacizumab on Corneal Endothelium
Study Status: Completed
Recruit Status: Unknown status
Study Type: Observational
Official Title: Effect of Intravitreal Bevacizumab on Corneal Endothelium
Brief Summary: To evaluate corneal endothelium cell change after intravitreal Bevacizumab injection
Detailed Summary: Intravitreal Bevacizumab has been used by retinal specialist in treatment many retinal diseases. Although it not approved by FDA for treatment. In many In vitro studies, its showed saftey in the eyes especially for corneal endothelium cells, that important cells to keep cornea clear. This study use Confoscan-Corneal confocal microsope to evaluate corneal endothelium before and after intravitreal Bevacizumab injection in routine retinal disease at 6 month follow up.
Sponsor: Khon Kaen University
Current Primary Outcome: Corneal endothelium cell change after intravitreal Bevacizumab injection [ Time Frame: 6 months ]
Original Primary Outcome: Same as current
Current Secondary Outcome: Assess the complication after intravitreal Bevacizumab injection [ Time Frame: 6 month ]
Original Secondary Outcome: Same as current
Information By: Khon Kaen University
Dates:
Date Received: November 11, 2012
Date Started: August 2011
Date Completion: October 2013
Last Updated: November 11, 2012
Last Verified: November 2012