Clinical Trial: Joint Stiffness Following Knee Replacement Surgery

Study Status: Withdrawn
Recruit Status: Withdrawn
Study Type: Observational

Official Title: Capsular Changes in Joint Contractures Post-Knee Arthroplasty:A Case-Control Study

Brief Summary: Our primary research question is to find out whether there is a genetic component to the development of joint contractures following knee surgery, through the application of lab techniques.

Detailed Summary: After total knee replacement surgery, some people develop joint stiffness, which is also called a joint contracture. Contractures cause the envelope of the knee (called the capsule) to stiffen and become rigid so the patient can no longer move their knee the way they used to. After stretching and other exercises, only a surgery can try and divide or remove the contracture. The main purpose of this research is to study the cause of the contracture and specifically if certain people are predisposed to contractures.
Sponsor: Ottawa Hospital Research Institute

Current Primary Outcome: Gene expression [ Time Frame: Dec 2015 ]

Original Primary Outcome:

Current Secondary Outcome:

Original Secondary Outcome:

Information By: Ottawa Hospital Research Institute

Dates:
Date Received: April 21, 2008
Date Started: December 2006
Date Completion:
Last Updated: April 22, 2015
Last Verified: April 2015