Clinical Trial: Topical Treatment of Bacterial Conjunctivitis and Its Effect on Microbial Flora

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: Topical Treatment of Bacterial Conjunctivitis and Its Effect on Microbial Flora

Brief Summary: Topical Treatment of Bacterial Conjunctivitis and its Effect on Microbial Flora

Detailed Summary:
Sponsor: Alcon Research

Current Primary Outcome:

  • Susceptability Changes in Streptococcus Pneumoniae Distal to the Site of Instillation [ Time Frame: Day 0 and Day 42 ]

    Susceptibility change refers to a change in vulnerability of a specified bacterial strain to antibiotic treatment. Susceptibility was assessed by broth microdilution methods recommended by the Clinical and Laboratory Standards Institute (CLSI).

    0% = zero isolates were resistant to antibiotic 100% = all isolates were resistant to antibiotic

  • Susceptability Changes in Staphylococcus Aureus Distal to the Site of Instillation [ Time Frame: Day 0, Day 42 ]

    Susceptibility change refers to a change in vulnerability of a specified bacterial strain to antibiotic treatment. Susceptibility was assessed by broth microdilution methods recommended by the Clinical and Laboratory Standards Institute (CLSI).

    0% = zero isolates were resistant to antibiotic 100% = all isolates were resistant to antibiotic

  • Susceptability Changes in Haemophilus Influenzae Distal to the Site of Instillation [ Time Frame: Day 0, Day 42 ]

    Susceptibility change refers to a change in vulnerability of a specified bacterial strain to antibiotic treatment. Susceptibility was assessed by broth microdilution methods recommended by the Clinical and Laboratory Standards Institute (CLSI).

    0% = zero isolates were resistant to antibiotic 100% = all isolates were resistant

    Original Primary Outcome: Susceptability changes in specified bacteria in the nasal cavity, oropharynx or skin when measured

    Current Secondary Outcome:

    Original Secondary Outcome:

    Information By: Alcon Research

    Dates:
    Date Received: April 4, 2006
    Date Started: June 2006
    Date Completion:
    Last Updated: October 31, 2012
    Last Verified: February 2010