Clinical Trial: In Vivo Optical Spectroscopy Monitoring in a New Model of Muscular Compartment Syndrome

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: In Vivo Optical Spectroscopy Monitoring in a New Model of Muscular Compartment Syndrome.

Brief Summary:

Muscular compartment syndrome (MCS) is consecutive to an increase in intramuscular compartment pressures, and is a rare but serious postoperative complication.

The INVOS (In Vivo Optical Spectroscopy) monitors tissular oxygenation continuously and non-invasively.

The objective is to develop a model mimicking the physiopathology of MCS to assess the interest of the INVOS in this case.

Detailed Summary: After inflation of a tourniquet (pressure equal to the mean arterial pressure, we will obtain a model of slight venous congestion and arterial hypoperfusion. A comparison will be made between INVOS monitoring, sensory deficits, pain, electromyography and invasive pressure.
Sponsor: Université Catholique de Louvain

Current Primary Outcome:

• Comparison Between INVOS Monitoring and Electromyography [ Time Frame: 45 minutes ]

  A comparison will be made between the INVOS monitoring and non invasive (transcutaneous) EMG monitoring (AP Block), to determine the accuracy of the INVOS monitoring to predict AP block.

  Measures were:

  [mean (SD)] INVOS (in %) value at baseline and at the time of the block

• Intracompartmental Pressure (ICP) [ Time Frame: 45 minutes ]
  [mean (SD)] ICP (in mmHg), value at baseline and at the time of the block

Original Primary Outcome: Comparison Between INVOS Monitoring and Electromyography [ Time Frame: 45 minutes ]

Current Secondary Outcome:

Original Secondary Outcome:

Information By: Université Catholique de Louvain

Dates:
Date Received: October 11, 2011
Date Started: October 2011
Date Completion:
Last Updated: December 15, 2014
Last Verified: December 2014