Clinical Trial: Chlorhexidine Impregnated Cloths to Prevent Skin and Soft Tissue Infections in Marine Officer Candidates
Study Status: Completed
Recruit Status: Completed
Study Type: Interventional
Official Title: Chlorhexidine Impregnated Cloths to Prevent Skin and Soft Tissue Infections in Marine Officer Candidates: A Randomized, Double-Blind, Placebo-Controlled Trial
Brief Summary:
Outbreaks of skin and soft tissue infections (SSTI) related to community associated Methicillin-resistant Staphylococcus aureus (MRSA) have become increasingly common in military training units. Risk factors for MRSA related SSTI such as crowding, poor hygiene and shared equipment are often hard to avoid in a military training environment, often designed to simulate battlefield conditions.
It has recently been demonstrated that military recruits colonized with MRSA may be at increased risk of developing SSTI. Studies in the hospital environment have shown that decolonizing inpatients known to carry MRSA decreases the rates of MRSA related infections in the treated individuals and also in their inpatient unit as a whole.
The investigators propose a randomized, double blind, placebo controlled trial to:
- Evaluate the effectiveness, feasibility, and safety of chlorhexidine body cloths, self-administered three times weekly, in preventing SSTI among recruits in military training facilities; and
- Evaluate the effectiveness of chlorhexidine body cloths in decreasing rates of Staphylococcus aureus colonization among military recruits.
Detailed Summary:
Sponsor: Uniformed Services University of the Health Sciences
Current Primary Outcome: The rate of skin and soft tissue infections among platoons enrolled in OCS. [ Time Frame: May - Nov 2007 ]
Original Primary Outcome:
Current Secondary Outcome: The rate of new S. aureus colonization of the nares and axilla among platoons enrolled in OCS. [ Time Frame: May- Nov 2007 ]
Original Secondary Outcome:
Information By: Uniformed Services University of the Health Sciences
Dates:
Date Received: May 18, 2007
Date Started: May 2007
Date Completion:
Last Updated: September 1, 2009
Last Verified: September 2009
