Clinical Trial: Implementation of a New Strategy to Identify HNPCC Patients

Study Status: Active, not recruiting
Recruit Status: Unknown status
Study Type: Interventional

Official Title: Cost Effectiveness of Two Different Implementation Procedures to Change Clinicians Practice Roles in the Detection of Hereditary Colorectal Cancer

Brief Summary: The purpose of this study is to compare two different strategies to implement a new method to identify patients with HNPCC, which appeared cost-effective and feasible. The effectiveness, costs and feasibility of both of the implementation strategies will be assessed.

Detailed Summary: The Radboud University Nijmegen Medical Centre developed a new method to identify patients with HNPCC. This method appeared cost-effective and feasible. Using this new method 70% of the HNPCC patients will be identified as compared to less than 30% when the current method is used. However, this new method does not implement itself; large gaps exists between best evidence and daily practice. This study will compare an intensive strategy, consisting of distribution of educational materials, education, feedback and reminders, with a minimal strategy, only consisting of distribution of a critical care pathway. The aim is to find the most cost-effective strategy to implement the new method to identify patients with HNPCC in the Netherlands.
Sponsor: Radboud University

Current Primary Outcome:

  • Efficacy of inclusion of eligible CRC-patients for MSI testing by pathologists.
  • Efficacy of referral of patients who are MSI positive to a clinical geneticist by surgeons.


Original Primary Outcome: Same as current

Current Secondary Outcome:

  • Experiences with and acceptance of changed physician practice roles by patients and clinicians.
  • Cost efficacy of the implementation procedures.


Original Secondary Outcome: Same as current

Information By: Radboud University

Dates:
Date Received: August 31, 2005
Date Started: September 2005
Date Completion: July 2007
Last Updated: April 22, 2008
Last Verified: February 2007