Clinical Trial: Cathartic-Free DECT Colonography for Detection of Colonic Polyps

Study Status: Terminated
Recruit Status: Terminated
Study Type: Observational

Official Title: Cathartic-Free Dual Energy Computerized Tomography (DECT) Colonography.

Brief Summary: Asses the clinical performance of dual-energy CTC for the detection of larger polyps 1 cm or larger without cathartic preparation.

Detailed Summary:

Determine the feasibility to differentiate polyps from stool with or without the use of contrast agents and to assess the feasibility and accuracy of dual energy techniques in a pilot patient study.

1.1 Formulate algorithms that use dual-energy information to quantitatively measure specific material density of colon polyps in physics based simulation.

1.2 Determine optimal scanning parameters on prototype CT equipment.

2.1 Measure the material composition density and Hounsfield number of polyps with and without simulated contrast enhancement.

2.2 Measure the accuracy of dual-energy techniques to differentiate between polyps and stool and if needed using a combination of simulated intravenous enhanced polyps and contrast material tagged stool.

3.0 Asses the clinical performance of dual-energy CTC for the detection of larger polyps 1 cm or larger without cathartic preparation.


Sponsor: Mayo Clinic

Current Primary Outcome: Clinical performance of dual-energy CT colonography (CTC). [ Time Frame: Three Months ]

Detection of polyps in cathartic-free CTC using optimized dual-energy techniques.


Original Primary Outcome:

Current Secondary Outcome:

Original Secondary Outcome:

Information By: Mayo Clinic

Dates:
Date Received: December 21, 2007
Date Started: February 2007
Date Completion:
Last Updated: January 20, 2016
Last Verified: January 2016