Clinical Trial: Prize Reinforcement Contingency Management for Cocaine Dependence: a 24-week Randomized Controlled Trial

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: Prize Reinforcement Contingency Management for Cocaine Dependence: a 24-week Randomized Controlled Trial

Brief Summary: The purpose of this study is to determine whether prize-based contingency management (prizeCM) combined with cognitive behavioral therapy (CBT) is more effective in the treatment of of cocaine-dependent patients compared to CBT only. Patients were randomized to prizeCM + CBT (experimental group) or to CBT (control group) an treated over 24 weeks. It is the first trial of this type in Europe.

Detailed Summary:
Sponsor: University Hospital, Basel, Switzerland

Current Primary Outcome: retention in treatment, cocaine abstinence [ Time Frame: 24 weeks ]

cocaine abstinence: at least 3 consecutive weeks of cocaine abstinence, the maximum number of weeks of continous abstinence and proportions of cocaine-free urine samples during the entire 24-week and at 6-month follow-up.


Original Primary Outcome: cocaine abstinence, retention in treatment [ Time Frame: 24 weeks ]

Current Secondary Outcome: patients' satisfaction with the therapy, clinical measures [ Time Frame: 24 weeks ]

patients' satisfaction with prize-based contingency management and with CBT


Original Secondary Outcome: satisfaction with the therapy [ Time Frame: 24 weeks ]

Information By: University Hospital, Basel, Switzerland

Dates:
Date Received: April 6, 2009
Date Started: September 2008
Date Completion:
Last Updated: January 28, 2015
Last Verified: January 2015