Clinical Trial: Scars After Central Venous Catheters
Study Status: Recruiting
Recruit Status: Unknown status
Study Type: Interventional
Official Title: Topical Treatment With Glucocorticoids to Prevent Hypertrophic Scars and Keloid Due to Central Venous Access in Children
Brief Summary:
Most children with cancer need a central venous catheter. These catheters are typically placed on the anterior thorax, where the risk of hypertrophic scarring and keloid development is greatly enhanced. A significant part of the children who have survived childhood cancer are troubled by their scars.
Topical glucocorticoid treatment is known to induce a reduction of the collagen in the connective tissue.
The investigators hypothesize that treatment with topical glucocorticoids for one week before and three weeks after removal of a central venous catheter, will reduce the formation of hypertrophic scarring and keloid development in children.
Detailed Summary:
Sponsor: Mette Møller Handrup
Current Primary Outcome: scars measured by the Vancouver Scar Scale twelve months after central venous catheter removal [ Time Frame: Twelve months ]
Original Primary Outcome: Same as current
Current Secondary Outcome:
- Judgement of the scar by Patient and observer scar scale after six months [ Time Frame: six months ]
- Judgement of the scar by Patient and observer scar scale after twelve months [ Time Frame: twelve months ]
- scars measured by the Vancouver Scar Scale six months after central venous catheter removal [ Time Frame: six months ]
Original Secondary Outcome: Same as current
Information By: Aarhus University Hospital
Dates:
Date Received: April 27, 2010
Date Started: March 2010
Date Completion: July 2016
Last Updated: February 11, 2014
Last Verified: February 2014
