Clinical Trial: The Use of Botulinum Toxin in the Treatment of Itching From Hypertrophic Scar -- A Randomised Controlled Trial

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Interventional

Official Title: The Use of Botulinum Toxin in the Treatment of Itching From Hypertrophic Scar -- A Randomised Controlled Trial

Brief Summary: Hypertrophic scar, a disfiguring tissue reaction to trauma, occurred in around 20 % of the population. The patients with hypertrophic scar usually seek medical assistance not just for the annoying appearance but mostly due to the intractable itchiness. There have been a variety of effective methods to alter the appearance of the scar. However, the treatments for itching from hypertrophic scar are scarce. In 2009, P.Gazerani used Botox to treat histamine-induced itch with favorable results. In the clinical setting, however, the efficacy of Botox to treat itch from hypertrophic scar was yet to be proven. Therefore, the goal of this study is to conduct a randomized controlled trials about using Botox to treat itch from hypertrophic scar.

Detailed Summary:
Sponsor: Kaohsiung Veterans General Hospital.

Current Primary Outcome: The degree of itchiness [ Time Frame: 6 months ]

Original Primary Outcome: Same as current

Current Secondary Outcome: Pain scale [ Time Frame: Within one minue after drug injection ]

Original Secondary Outcome: Same as current

Information By: Kaohsiung Veterans General Hospital.

Dates:
Date Received: March 11, 2014
Date Started: November 2013
Date Completion:
Last Updated: October 7, 2015
Last Verified: October 2015