Clinical Trial: Safety and Efficacy of Bone Marrow Derived MNCs for Treatment of Cells for the Treatment of Hunting Tons Chorea.
Study Status: Completed
Recruit Status: Unknown status
Study Type: Interventional
Official Title: Safety and Efficacy of Bone Marrow Derived MNCs for the Treatment of Huntingtons Chorea. It is Self Funded (Patients' Own Funding) Clinical Trial
Brief Summary: This study is Single arm, Single Centre trial to check the Safety and Efficacy of Bone Marrow Derived Autologous mononuclear cell {MNC} (100 Million per dose).trial to be conducted for 36 months in patients with diabetes Mellitus in India,Primary outcome measure are Improvement in cognitive and Psychiatric Symptoms and Improvement in Jerky,random, and Uncontrollable Movements called Chorea.
Detailed Summary: This study is Single arm, Single Centre trial study the Safety and Efficacy of Bone Marrow Derived Autologous mononuclear cells (MNCs) ,to be conducted for 36 months in patients with diabetes Mellitus in India,Primary outcome measure are Improvement in cognitive and Psychiatric Symptoms and Improvement in Jerky,random, and Uncontrollable Movements called Chorea.
Sponsor: Chaitanya Hospital, Pune
Current Primary Outcome: Improvement in Cognitive and psychiatric symptoms [ Time Frame: 6 Months ]
Original Primary Outcome: Same as current
Current Secondary Outcome:
- Improvement in neuropsychiatric behaviour [ Time Frame: 6 Months ]
- Increase in life expectancy [ Time Frame: 6 Months ]Increase in life expectancy.Time period- 6 Months
- Improvement in writhing motions or abnormal posturing [ Time Frame: 6 month ]-Improvement in writhing motions or abnormal posturing
- Improvement in compulsive behaviour [ Time Frame: 6 month ]
Original Secondary Outcome: Same as current
Information By: Chaitanya Hospital, Pune
Dates:
Date Received: April 11, 2013
Date Started: September 2014
Date Completion: June 2016
Last Updated: September 16, 2014
Last Verified: September 2014
