Clinical Trial: Retrospective Review of CT and MR in Pediatric Patients With Cholestasis

Study Status: Enrolling by invitation
Recruit Status: Unknown status
Study Type: Observational

Official Title: Retrospective Review of Computed Tomography and Magnetic Resonance Images in Pediatric Patients With Cholestasis

Brief Summary: The investigators will try to predict the risk of esophageal varices (EVs) in long-term BA survivors using noninvasive computed tomography (CT) or magnetic resonance (MR) indices and the measurement of transverse diameters of paraesophageal and gastroesophageal veins.

Detailed Summary:

We intend to review retrospectively 80 pediatric patients on an average of 2 years, who underwent 64-slice CT or MR examinations between January 2005 and Oct 2010 and had EVs on esophagogastroduodenoscopy. Splenic diameters (mm) and hepatic diameters of all patients were measured. Splenic and hepatic volume indices also calculated. The transverse diameters of paraesophageal varices (PVs) and perigastric varices (PGVs) were measured adjacent to the lower thoracic esophagus and within the lesser sac, respectively.

We will try to find out the possible splenic, hepatic or vascular predicting factors useful to evaluate the risk of clinically evident esophageal varices.

Sponsor: National Taiwan University Hospital

Current Primary Outcome: esophageal variceal bleeding [ Time Frame: retrospective review ]

Original Primary Outcome: Same as current

Current Secondary Outcome:

Original Secondary Outcome:

Information By: National Taiwan University Hospital

Dates:
Date Received: November 25, 2010
Date Started: October 2010
Date Completion: October 2011
Last Updated: November 30, 2010
Last Verified: November 2010