Clinical Trial: Gentamicin in Preventing Post Endoscopic Retrograde Cholangiopancreatography (ERCP) Cholangitis in Non-calculus Stenting

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: Comparing Addition of Gentamicin vs. Placebo in Preventing Post ERCP Cholangitis in Non-calculus Stenting

Brief Summary: Cholangitis is the most prevalent infectious complication of ERCP. Stenting of biliary strictures and stenosis is one of important risk factors for post-ERCP cholangitis. Adding antibiotics to contrast media has proposed in some studies for prevention of cholangitis but remains controversial. In this study we compare effect of adding gentamicin versus placebo in preventing cholangitis in patients who undergone endoscopic stenting for non-calculus strictures and stenosis.

Detailed Summary:
Sponsor: Tehran University of Medical Sciences

Current Primary Outcome: Number of Participants With Cholangitis [ Time Frame: 72 hours ]

After Endoscopic Retrograde CholangioPancreatography (ERCP) in 3 following days we check all participants for syptoms of cholangitis (fever, chills, right upper qudrant (RUQ) pain, leukocytosis) and ruling out other diagnoses than cholangitis


Original Primary Outcome: cholangitis [ Time Frame: 72 hours ]

After ERCP in 3 following days we check for fever, chills, RUQ pain, leukocytosis and ruling out other diagnoses than cholangitis


Current Secondary Outcome:

Original Secondary Outcome:

Information By: Tehran University of Medical Sciences

Dates:
Date Received: June 19, 2010
Date Started: December 2009
Date Completion:
Last Updated: September 18, 2011
Last Verified: July 2011