Clinical Trial: Acceptability of a Multiple Micronutrient-Fortified Lipid-Based Nutrient Supplement for Children Under Two in Cambodia

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: Acceptability of a Locally-Produced Multiple Micronutrient-Fortified Lipid-Based Nutrient Supplement (LNS) for Children Under Two Years in Cambodia

Brief Summary: The purpose of this trial is to evaluate the acceptability of the LNS to women and their children aged 12-17 months in comparison to Corn Soy Blend++, and Sprinkles added to borbor (white rice porridge, which is the traditional weaning food in Cambodia). Acceptability will be assessed through a sensory test for caregivers, and by measuring children's consumption.

Detailed Summary:

BACKGROUND:

In Cambodia, progress in combatting malnutrition has stalled. In 2010, 40% of all children under five (and 49% of 4-5 year-olds) were stunted, 11% were wasted, and 28% were underweight, indicating, respectively, chronic and acute malnutrition, and a combination of the two. Stunting is partially attributed to poor complementary feeding, which remains inadequate for achieving growth outcomes and micronutrient status.

Malnutrition can be prevented and treated with supplementary foods. These foods usually contain a source of protein and lipids such as powered milk, soy or peanuts, and multiple micronutrients. They can be prepared as a fortified blended product, such as Corn-Soy Blend++ (CSB++), that is mixed with water to make a porridge, or ready-to-use supplementary foods (RUSFs). The latter are usually lipid-based nutrient supplements (LNSs) which are often pastes such as the peanut-based Plumpy'Nut™. These energy-dense supplementary foods contain both macro and micronutrients and are used to prevent and treat malnutrition by promoting improved linear growth, weight gain and micronutrient status among children. Until recently, prevention of malnutrition has relied on fortified blended products. The new RUSFs are also proving effective, as they are higher energy and have a longer shelf life, and since they require no preparation, are convenient. Another common nutrition intervention is multiple micronutrient supplements such as Sprinkles. These are individually-packed powders that can be added to food. However, micronutrients are more likely to achieve growth outcomes when they are combined with energy, for example, in lipid-based nutrient supplements and there is no evidence that micronutrient powders alone contribute to growth.

Until June 2014, the United
Sponsor: Institut de Recherche pour le Developpement, Cambodia

Current Primary Outcome: Child's consumption [ Time Frame: Within 15 minutes ]

How much of a given food the children consume


Original Primary Outcome: Same as current

Current Secondary Outcome:

  • Child's preference [ Time Frame: 3 days ]
    Mothers' assessment of their child's ranked preference for the food
  • Mother's ranking [ Time Frame: 1 session ]
    Mother's ranked preference for the food


Original Secondary Outcome: Same as current

Information By: Institut de Recherche pour le Developpement, Cambodia

Dates:
Date Received: October 2, 2014
Date Started: June 2015
Date Completion:
Last Updated: September 13, 2016
Last Verified: September 2016