Clinical Trial: Population Pharmacokinetics in Benznidazole-treated Adults With Chronic With Chagas Disease

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: Population Pharmacokinetics in Benznidazole-treated Adults With Chronic Chagas Disease. Benznidazole Pharmacokinetics and Adverse Reactions Relationship.

Brief Summary: o study population pharmacokinetics in Benznidazole-treated adult patients with Chronic Chagas Disease to get information to optimize drug doses.

Detailed Summary:
Sponsor: Barcelona Centre for International Health Research

Current Primary Outcome: Population pharmacokinetic parameters of Benznidazole [ Time Frame: 2 months (treatment period) ]

Population pharmacokinetic model development


Original Primary Outcome: Same as current

Current Secondary Outcome: Adverse reactions [ Time Frame: 2 months (treatment period) ]

Number of participants with adverse events. Severity of adverse events. Relationship between adverse event and drug concentration.


Original Secondary Outcome: Same as current

Information By: Barcelona Centre for International Health Research

Dates:
Date Received: December 19, 2012
Date Started: December 2012
Date Completion:
Last Updated: May 25, 2015
Last Verified: May 2015