Clinical Trial: Assessment of Speckle Tracking Strain Predictive Value for Myocardial Fibrosis in Chagas Disease

Study Status: Completed
Recruit Status: Completed
Study Type: Observational

Official Title: Assessment of Speckle Tracking Strain Predictive Value for Myocardial Fibrosis in Subjects With Chagas Disease

Brief Summary: One of the most challenging issues of chronic Chagas disease is to provide earlier detection of heart involvement. Two-dimensional speckle tracking (2-D ST) echocardiography, a new imaging modality with useful applications in several cardiac diseases, has been validated for subjects with myocardial infarction against cardiac magnetic resonance (CMR). Here the investigators hypothesize that the longitudinal global strain (LGS) has an incremental value to ejection fraction for predicting myocardial fibrosis in subjects with Chagas disease.

Detailed Summary:
Sponsor: Hospital Sao Rafael

Current Primary Outcome: Correlation between longitudinal global strain and the percentage of myocardial fibrosis. [ Time Frame: The outcome measure will be assessed within one month of follow up. ]

We will correlate longitudinal global strain and the percentage of myocardial fibrosis (Spearman correlation).


Original Primary Outcome: Same as current

Current Secondary Outcome:

Original Secondary Outcome:

Information By: Hospital Sao Rafael

Dates:
Date Received: December 18, 2014
Date Started: January 2011
Date Completion:
Last Updated: December 29, 2014
Last Verified: December 2014