Clinical Trial: Value of Radionuclide Cisternography

Study Status: Completed
Recruit Status: Completed
Study Type: Observational

Official Title: VALUE OF RADIONUCLIDE CISTERNOGRAPHY IN PATIENTS WITH CEREBROSPINAL FLUID LEAK

Brief Summary:

Radionuclide cisternography (RC) is a nuclear medicine examination based on intrathecal injection of [111In]diethylenetriaminepentaacetic acid ([111In]DTPA). It is prescribed for two recommendations: detection of cerebrospinal fluid (CSF) leak/fistula and diagnosis of normal pressure hydrocephalus.

In the search part of CSF leak/fistula, RC offers the benefit of a 24-hour study of CSF unlike other reference tests.

In addition to SPECT/CT imaging, the radiopharmacist performs sampling in nasal cavities and throat of the patient to collect a possible flow of CSF.

These samples are analysed by radioactivity measurements and bring an added value to the exam.

The interest of this examination for management of CSF leak/fistula remains unclear.

The aim of this study is to identify and analyse results of all RC examinations performed since 2005 in the Nuclear Medicine department of the Neurological Hospital.

The full analysis of patients will allow discussing the role of RC in management of CSF leak/fistulae in clinical practice.


Detailed Summary:
Sponsor: Hospices Civils de Lyon

Current Primary Outcome: RC /SPECT/CT imaging [ Time Frame: one week ]

Results of RC including results of SPECT/CT imaging and results of swabs counting (nasal cavities and throat or ear if applicable)


Original Primary Outcome: Same as current

Current Secondary Outcome:

Original Secondary Outcome:

Information By: Hospices Civils de Lyon

Dates:
Date Received: August 9, 2016
Date Started: January 2005
Date Completion:
Last Updated: August 18, 2016
Last Verified: August 2016