Clinical Trial: Improving Platelet Activity for Cerebral Hemorrhage Treatment - DDAVP Proof of Concept
Study Status: Completed
Recruit Status: Completed
Study Type: Interventional
Official Title: Improving Platelet Activity for Cerebral Hemorrhage Treatment - DDAVP Proof of Concept
Brief Summary: The investigators intend to show that DDAVP improves platelet activity from baseline to 60 minutes after treatment start.
Detailed Summary:
Sponsor: Northwestern University
Current Primary Outcome: Change in Platelet Activity, Measured in Seconds on PFA-EPI Assay, From Pre to Post-treatment [ Time Frame: 60 minutes after treatment start ]
Original Primary Outcome: Platelet activity, measured in aspirin reaction units [ Time Frame: 30-60 minutes after treatment ]
Current Secondary Outcome: Adverse Events : New Fever >=100.4F, Respiratory Distress or Pulmonary Edema on Chest Radiography, Rash, Hypotension (Systolic BP < 100 mm Hg or New Vasopressor Use or Increase in Vasopressor Dose by >25%) [ Time Frame: within 6 hours of study treatment ]
Original Secondary Outcome: Adverse Events : New Fever >=100.4F, Respiratory Distress or Pulmonary Edema on Chest Radiography, Rash, Hypotension (Systolic BP < 100 mm Hg or New Vasopressor Use or Increase in Vasopressor Dose by >25%) [ Time Frame: within 4 hours of study treatment ]
Information By: Northwestern University
Dates:
Date Received: August 17, 2009
Date Started: December 2010
Date Completion:
Last Updated: August 11, 2014
Last Verified: July 2014