Clinical Trial: Comparison of Multifocal Electroretinogram Assessment in Chronic Central Serous Chorioretinopathy (CSC) Between Laser Treatment Group and Photodynamic Therapy Group in Chronic Central Serous Chorioretinopathy
Study Status: Completed
Recruit Status: Completed
Study Type: Observational
Official Title: Comparison of Multifocal Electroretinogram Assessment Between Laser Treatment Group and Photodynamic Therapy Group in Chronic Central Serous Chorioretinopathy
Brief Summary: This study is a comparison of multifocal electroretinogram assessment between the laser treatment group and the photodynamic therapy group in chronic central serous chorioretinopathy.
Detailed Summary:
- Laser Group: extrafoveal focal leakage on FAG
- PDT Group: no definite focal leak on FAG subfoveal or juxtafoveal focal leakage on FAG, or serous retinal pigmentary epithelial detachment involving foveal center
Inclusion criteria
- Chronic serous chorioretinopathy (over 3 months) when subretinal fluid persisted in the subfoveal region demonstrated by clinical examination and OCT
- Ability to maintain steady fixation for mfERG
- Presence of abnormal dilated choroidal vasculature in ICGA
- Symptom duration over 3 months
Exclusion criteria
- previous PDT or laser treatment history
- evidence of Choriinal neovascularization in FAG
- other chorioretinal disorders that can cause macular exudation such as age-related macular degeneration, pathologic myopia, angioid streaks, trauma, inflammatory diseases, retinal vasculopathies, and hereditary dystrophies
follow-up Visit
1)baseline 2)1month 3)3months 4)6 months
each visit: multifocal electroretinogram, visual acuity, optical coference timography should be measured.
Sponsor: Samsung Medical Center
Current Primary Outcome: Multifocal Electroretinogram Amplitudes [ Time Frame: baseline, 1 month, 3 months, 6 months ]
Original Primary Outcome: Multifocal Electroretinogram Amplitudes [ Time Frame: baseline, 1 month, 3 months 6 months ]
Current Secondary Outcome: Best Corrected Visual Acuity [ Time Frame: baseline, 1 month, 3 months, 6 months ]
Original Secondary Outcome: Same as current
Information By: Samsung Medical Center
Dates:
Date Received: November 12, 2008
Date Started: March 2008
Date Completion:
Last Updated: March 11, 2009
Last Verified: February 2009