Clinical Trial: Quality Control: A Prospective Analysis of EVD Effectiveness

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Interventional

Official Title: Quality Control: A Prospective Analysis of External Ventricular Drain (EVD) Effectiveness

Brief Summary: The purpose and/or hypothesis: To decrease the amount of external ventricular drain (EVD) related catheter infections by comparing the efficacy of Oklahoma University Medicine standard EVD catheters, both impregnated and non-impregnated, in three principle areas: incidence of infection, cost analysis, and average durations of placement, all while maintaining the standards of technique.

Detailed Summary:

Experimental design: Track external ventricular drain (EVD) associated infections and through quality prospective analysis and compare the usage of standard catheters used by the department here at Oklahoma University, 1) the 35cm Codman Bactiseal rifampin and clindamycin impregnated catheter, 2) the Ventriclear EVD Antibiotic Catheter, and 3) the 36 cm Integra Hermatic large style ventricular catheter, in terms of incidence of infections, cost, duration of placement, and differences in placement technique.

Proposed procedure: Monitor for infections associated with and related to EVD placement in patients and assess if infections rates are affected by usage of antibiotic impregnated EVD catheters.

Importance of knowledge reasonably expected to result from the research: While use of sterile techniques and periprocedural antibiotics have traditionally been used to combat infection, infection rates remain above goal leading to the question of whether the antibiotic impregnated catheter should be added to the standard of care. With the knowledge gained, the investigators hope to decrease the amount of external ventricular drain related catheter infections and reduce use of prolonged antibiotics.

Sponsor: University of Oklahoma

Current Primary Outcome: Infection rates of EVD patients [ Time Frame: 24 months ]

Original Primary Outcome: Same as current

Current Secondary Outcome: Cost comparison between 3 EVDs utilizing data received from billing [ Time Frame: 24 months ]

Original Secondary Outcome: Same as current

Information By: University of Oklahoma

Dates:
Date Received: June 23, 2015
Date Started: April 2016
Date Completion: July 2018
Last Updated: June 8, 2016
Last Verified: June 2016