Clinical Trial: Absorption of Brimonidine Ophthalmic Solution in the Aqueous Humor of Cataract Patients

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: Absorption of Brimonidine Ophthalmic Solution in the Aqueous Humor of Cataract Patients.

Brief Summary: The purpose of this study is to obtain and assay human aqueous samples following pre-operative dosing with 0.1% Brimonidine Purite™ (pH 7.8) or with 0.15% Brimonidine Purite® (pH 7.2) from patients undergoing routine cataract surgery in order to evaluate the aqueous concentration of the two formulations.Study hypothesis: The aqueous humor concentration 45 minutes following dosing of 0.1% Brimonidine Purite™ (pH 7.8) is comparable with 0.15% Brimonidine Purite® (pH 7.2)

Detailed Summary: The purpose of this study is to obtain and assay human aqueous samples following pre-operative dosing with 0.1% Brimonidine Purite™ (pH 7.8) or with 0.15% Brimonidine Purite® (pH 7.2) from patients undergoing routine cataract surgery in order to evaluate the aqueous concentration of the two formulations.
Sponsor: Indiana University School of Medicine

Current Primary Outcome: Bioanalysis of brimonidine concentrations.

Original Primary Outcome: Same as current

Current Secondary Outcome:

Original Secondary Outcome:

Information By: Indiana University

Dates:
Date Received: July 14, 2006
Date Started: February 2005
Date Completion: December 2005
Last Updated: October 16, 2007
Last Verified: October 2007