Clinical Trial: Gabapentin for Carpal Tunnel Syndrome
Study Status: Completed
Recruit Status: Completed
Study Type: Interventional
Official Title: Gabapentin for Carpal Tunnel Syndrome: A Randomised Controlled Trial
Brief Summary: The purpose of this study is to determine whether gabapentin is safe and effective in the treatment of carpal tunnel syndrome (CTS).
Detailed Summary: A variety of treatment options exist at present for carpal tunnel syndrome (CTS) with no universal agreement. Recent reports suggested that untreated CTS might improve or remain stationary. In this respect, treatment directing towards symptom suppression alone may have a role in the initial management of CTS. Gabapentin (1-[aminomethyl]-cyclohexaneacetic acid; Neurontin, Pfizer) is an effective drug for treatment of neuropathic pain and has been reported to be effective in case series for the treatment of CTS with relatively benign side effects profile. The purpose of this study was to evaluate the safety and efficacy of gabapentin in the treatment of CTS.
Sponsor: Chinese University of Hong Kong
Current Primary Outcome: Global symptom score (GSS) recorded by a physician blinded to the allocation of treatment at 8 weeks [ Time Frame: 8 weeks ]
Original Primary Outcome: Global Symptom Score (GSS) recorded by a physician blinded to the allocation of treatment at 8 weeks.
Current Secondary Outcome:
- GSS at 2 weeks [ Time Frame: 2 weeks ]
- Grip strength as functional assessment at 2 and 8 weeks [ Time Frame: 2 weeks, 8 weeks ]
- Tolerability [ Time Frame: throughout subject's participation in trial ]
Original Secondary Outcome:
- 1) GSS at 2 weeks
- 2) Grip strength as functional assessment at 2 and 8 weeks
- 3) Tolerability
Information By: Chinese University of Hong Kong
Dates:
Date Received: August 29, 2005
Date Started: October 2003
Date Completion:
Last Updated: October 30, 2007
Last Verified: October 2007
