Clinical Trial: Detection of Chemotherapy Induced Cardiotoxicity
Study Status: Completed
Recruit Status: Completed
Study Type: Observational
Official Title: Detection of Chemotherapy Induced Cardiotoxicity
Brief Summary: To identify patients that are at risk of heart damage after receiving chemotherapy (adriamycin).
Detailed Summary: To identify patients at risk of development of heart damage after receiving chemotherapy by obtaining the genetic profile of those who show: elevation of troponin, left ventricular systolic and diastolic dysfunction, and pro-oxidant stress markers.
Sponsor: George Washington University
Current Primary Outcome: The genetic profile of patients with anthracycline-induced elevation of troponin-I [ Time Frame: one year ]
Original Primary Outcome: Same as current
Current Secondary Outcome:
- Assess the genetic profile of patient with anthracycline-induced left ventricular systolic and diastolic dysfunction [ Time Frame: one year ]
- Assess the relationship of quantitative increases of pro-oxidant stress and a specific genetic profile [ Time Frame: one year ]
Original Secondary Outcome: Same as current
Information By: George Washington University
Dates:
Date Received: March 10, 2008
Date Started: January 2008
Date Completion:
Last Updated: March 11, 2013
Last Verified: August 2012
