Clinical Trial: Noninvasive Ventilation and Thoracic-abdominal Kinematics in Heart Failure Patients

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: Effect of Noninvasive Ventilation in Thoracic-abdominal Kinematics of Individuals With Heart Failure Associated With Cardiomegaly: a Randomized Controlled Trial

Brief Summary: Introduction: Noninvasive ventilation (NIV) has been used to minimize such impairment and increasing ventilator reserve in individuals with heart failure. Aim: To analyze thoracoabdominal kinematics (TK) in individuals with HF associated to cardiomegaly after using NIV. Methods: A randomized crossover clinical trial with allocation consisted of two experimental phases: NIV and control, 7 days apart of each other. During NIV phase, 30 minutes of bi-level ventilation was performed. Any type of ventilator support was offered during control phase. Optoeletronic plethismography was performed to asses TK.

Detailed Summary:
Sponsor: Universidade Federal de Pernambuco

Current Primary Outcome: Thoraco-abdominal kinematics [ Time Frame: Seven days ]

The thoraco-abdominal kinematics was performed by optoelectronic plethysmography which were evaluated as primary outcomes: volume change of rib cage (Δv CT), variables related to volume change of rib cage by hemithorax (ΔV ht CT): tidal volume of cash left thoracic (CT VC sx) and tidal volume right ribcage (VC CT dx); variables with distribution volume in different compartments: tidal volume on pulmonary rib cage (VC CTP), tidal volume in abdominal rib cage (VC CTA ) and tidal volume in the abdomen (AB VC).


Original Primary Outcome: Same as current

Current Secondary Outcome: Other ventilatory responses [ Time Frame: Seven days ]

The other ventilatory responses were also assessed by optoelectronic plethysmography which were assessed as secondary outcomes: minute ventilation (MV); Inhalant rate (RR), duty cycle (Ti / Ttot), expiratory time (TE), end of rib cage (VEF CT) expiratory volume.


Original Secondary Outcome: Same as current

Information By: Universidade Federal de Pernambuco

Dates:
Date Received: February 25, 2014
Date Started: March 2013
Date Completion:
Last Updated: February 26, 2014
Last Verified: February 2014