Clinical Trial: Accelerated Partial Breast Irradiation Following Lumpectomy for Breast Cancer

Study Status: Active, not recruiting
Recruit Status: Active, not recruiting
Study Type: Interventional

Official Title: Accelerated Partial Breast Irradiation Following Lumpectomy for Breast Cancer

Brief Summary: To determine whether an accelerated course of radiotherapy delivered to the lumpectomy cavity plus margin using IORT as a single dose, intracavitary brachytherapy with the MammoSite device over 5 days, partial breast 3-D CRT in 5 days, or stereotactic APBI over 4 days is a feasible and safe alternative to a six and a half week course of whole breast radiotherapy. The study will measure both short and long-term complications of radiation treatment, short and long-term breast cosmesis, local rates of in-breast cancer recurrence, regional recurrences, distant metastases, and overall survival.

Detailed Summary:
Sponsor: Stanford University

Current Primary Outcome: In-breast tumor recurrence (IBTR) [ Time Frame: 20 years ]

Proportion of subjects that experience in-breast tumor recurrence (IBTR), to be assessed through or by March 2029


Original Primary Outcome:

Current Secondary Outcome:

Original Secondary Outcome:

Information By: Stanford University

Dates:
Date Received: September 12, 2005
Date Started: September 2002
Date Completion: March 2029
Last Updated: December 8, 2016
Last Verified: December 2016