Clinical Trial: Invasive Candidiasis in ICU

Study Status: Completed
Recruit Status: Unknown status
Study Type: Observational

Official Title: Invasive Candidiasis in Critically Ill Patients in Saudi Arabia: A Prospective Cohort Study

Brief Summary: Epidemiology and clinical outcomes of invasive candidiasis in critically ill patients in Saudi Arabia is not well studied. This observational study objectives include to determine the epidemiology, risk factors and outcomes of invasive Candida infection in critically ill patients in Saudi Arabia.

Detailed Summary:
Sponsor: Hasan Al-Dorzi

Current Primary Outcome: ICU mortality [ Time Frame: Patients will be followed while in the ICU and the vital status at the time of discharge from the ICU will be noted. The expected stay in the ICU is 10 days on average. ]

For patients staying in the ICU for long periods, ICU mortality will be censored at 180 days after entry into the study.That is patient staying alive in the ICU more than 180 days will be considered alive.


Original Primary Outcome: ICU mortality [ Time Frame: Patients will be followed while in the ICU and the vital status at the time of discharge from the ICU will be noted (expected stay is 10 days on average). ICU mortality will be censored at 180 days after entry into the study. ]

Current Secondary Outcome:

  • hospital mortality [ Time Frame: patients will be followed until discharge from the hospital and vital status at discharge from the hospital will be noted (expected hospital stay is 5 weeks). Hopsital mortality will be censored at 180 days after entry into the study. ]
    If patients are still alive at 180 days after entring the sudy, they will be considered hospital survivors.
  • duration of mechanical ventilation [ Time Frame: date of extubtation minus date of intubation ]
    If multiple intubations in the same admission, then the durations of mechanical ventilation will be added.This will be assessed for up to 180 days of stay in the ICU.
  • length of stay in the ICU [ Time Frame: date of discharge from ICU minus date of admission to ICU ]
    Patients will be followed for up to 180 days.Patinets alive in the ICU beyond 180 days of stay will have an ICU length of stay of 180 days.
  • length of stay in the hospital [ Time Frame: date of discharge from hospital minus date of admission to hospital ]
    Patients will be followed for up to 180 days.Patinets alive in the hospital beyond 180 days of stay will have a hospital length of stay of 180 days.


Original Secondary Outcome:

  • hospital mortality [ Time Frame: patients will be followed until discharge from the hospital and vital status at discharge from the hospital will be noted (expected hospital stay is 5 weeks). Hopsital mortality will be censored at 180 days after entry into the study. ]
  • duration of mechanical ventilation [ Time Frame: date of extubtation minus date of intubation ]
    If multiple intubations in the same admission, then durations will be added.
  • length of stay in the ICU [ Time Frame: date of discharge from ICU minus date of admission to ICU ]
  • length of stay in the hospital [ Time Frame: date of discharge from hospital minus date of admission to hospital ]


Information By: King Abdulaziz Medical City

Dates:
Date Received: December 2, 2011
Date Started: August 2012
Date Completion: January 2014
Last Updated: August 13, 2012
Last Verified: August 2012