Clinical Trial: Silent Breast Cancer A Study of the Disease Prevalence Held by Imaging Guided Biopsies in Autopsy Specimens

Study Status: Active, not recruiting
Recruit Status: Active, not recruiting
Study Type: Interventional

Official Title: Silent Breast Cancer A Study of the Disease Prevalence Held by Imaging Guided Biopsies in Autopsy Specimens

Brief Summary: The aim of this study is to define silent breast cancer prevalence in both sexes and will be held by biopsies performed in imaging suspicious areas of the breast (ecography and mammography) in cadavers without known breast cancer.

Detailed Summary:

Cadavers of both sexes are going to be submitted to bilateral mastectomy. The specimens are going to be examined by palpation, ecography and mammography and all areas with (Breast Imaging Reporting and Data System) BI-RADS classification >= 3 are going to be biopsied.

Biopsy specimens are going to be processed by the pathology department and cancers are going to be identified and classified by their molecular type.

The investigators intend to know which is the disease reservoir in various ages.


Sponsor: Centro Hospitalar Lisboa Ocidental

Current Primary Outcome: Silent breast cancer prevalence [ Time Frame: 2 years ]

To define the existing disease that did not caused death in both sexes


Original Primary Outcome: Same as current

Current Secondary Outcome: Silent breast cancer prevalent molecular profile [ Time Frame: 2 years ]

To identify those molecular subgroups of the disease that remain silent


Original Secondary Outcome: Same as current

Information By: Centro Hospitalar Lisboa Ocidental

Dates:
Date Received: June 17, 2015
Date Started: September 2016
Date Completion: September 2018
Last Updated: September 5, 2016
Last Verified: September 2016