Clinical Trial: Oxygen Toxicity of HBOT in Chronic Brain Injury

Study Status: Completed
Recruit Status: Unknown status
Study Type: Interventional

Official Title: Oxygen Toxicity Effects Using Los-Pressure Hyperbaric Oxygen Therapy in the Treatment of Chronic Brain Injury

Brief Summary: Hypothesis: That HBOT can be toxic in the low-pressure range.

Detailed Summary: The study is a retrospective review of the author's experience treating chronic brain injury with HBOT, supplemented by cases communicated to the author, who developed untoward effects during or after their HBOT. The object of the study was to affirm or refute the author's general impression that there was an optimal dose of HBOT in chronic brain injury which was lower than the traditional dose applied in chronic non-central nervous system wounding. Furthermore, when this lower dosage range was exceeded and approached the traditional doses for non-CNS wounding oxygen toxicity would result. To address these impressions the study seeks to review the author's medical records and other patient/doctor communications to the author where side effects of HBOT occurred in the treatment of chronic brain injury and abstract signs, symptoms, and the dose of HBOT employed.
Sponsor: Paul G. Harch, M.D.

Current Primary Outcome: Oxygen toxicity [ Time Frame: After completion of hyperbaric oxygen therapy ]

Original Primary Outcome: Oxygen toxicity [ Time Frame: 17 years ]

Current Secondary Outcome:

Original Secondary Outcome:

Information By: Louisiana State University Health Sciences Center in New Orleans

Dates:
Date Received: January 2, 2008
Date Started: April 2002
Date Completion: December 2016
Last Updated: January 1, 2015
Last Verified: January 2015