Clinical Trial: Intraoperative Volume Management and QT Interval
Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Observational
Official Title: Intraoperative Repolisarisation - Etiology and Relevance for the Decision Making by Anesthesiologists in the Management of Volume Substitution and Transfusion
Brief Summary: QT interval changes is measured during all phases of the operation. The protocol is focusing at intraoperative bleeding events and is also observing QT interval changes during anesthetic and operative procedures.
Detailed Summary: Prolongation of the QT interval is associated with functional torsade de points, re-entry, and sudden death (see reference). Variations of QT-interval caused by changes in the volume status of the patient during an operation remained unclear. QT interval changes will be monitored during the surgery with the focus of the influence of sudden blood loss, volume substitution by crystalloids, blood and blood products. The effect of surgical procedures on the QT-intervall (e.g. clamping of kidney artery) will be observed as well as the association of intra-operative QT-interval alterations with postoperative complications.
Sponsor: Technische Universität Dresden
Current Primary Outcome: change in QT-time [ Time Frame: during operation ]
Original Primary Outcome: Same as current
Current Secondary Outcome:
- postoperative incidents/disturbations rhythm of the heart [ Time Frame: 2 days ]association to intraoperative repolarisation-disturbations / QT-prolongation
- survival [ Time Frame: 1 year ]association to intraoperative repolarisation-disturbations / QT-prolongation
Original Secondary Outcome: Same as current
Information By: Technische Universität Dresden
Dates:
Date Received: May 8, 2015
Date Started: May 2015
Date Completion: December 2017
Last Updated: May 11, 2015
Last Verified: May 2015
