Clinical Trial: Eyelid Position Interdependence in Involutional Ptosis Patients Submitted to 10% Phenylephrine

Study Status: Completed
Recruit Status: Completed
Study Type: Observational

Official Title: Comparative Study of Eyelid Position Interdependence in Involutional Ptosis Patients Submitted to 1, 2 or 4 Drops of 10% Phenylephrine

Brief Summary: The primary aim of this study is to quantify eyelid position changes in tested and opposite eyes in ptosis patients submitted to 1, 2 or 4 drops of 10% phenylephrine in one eye. The secondary objective is to correlate the eye dominance, severity and laterality of ptosis with eyelid position changes in these 3 groups.

Detailed Summary:

This is a prospective observational study conducted in involutional ptosis patients, which will be submitted to instillation of a single drop of 10% phenylephrine in one eye(Group 1), 2 drops (G2) or 4 drops ( G3).

Video camera will record the images of both eyes before and after drug application at 3, 10, 15 and 30 minutes. The images will be edited to analyze upper and lower lid height.

Sponsor: University of Sao Paulo

Current Primary Outcome: Upper lid height before and after phenylephrine test lower lid height before and after phenylephrine test [ Time Frame: 3, 10, 15 and 30 minutes ]

Original Primary Outcome: Same as current

Current Secondary Outcome: Scobee test to detect eye dominance [ Time Frame: 15 minutes before 10% phenylephrine instillation ]

Original Secondary Outcome: Same as current

Information By: University of Sao Paulo

Dates:
Date Received: March 17, 2009
Date Started: September 2006
Date Completion:
Last Updated: March 18, 2009
Last Verified: March 2009