Clinical Trial: Risk of Dry Eye Post Different Surgeries for Blepharoptosis Repair

Study Status: Not yet recruiting
Recruit Status: Not yet recruiting
Study Type: Interventional

Official Title: Comparison Between Three Different Surgeries for Blepharoptosis Repair and Their Impact on Dry Eye Status

Brief Summary: Blepharoptosis, inferodisplacement of the upper eyelid, can be congenital or acquired. Acquired Blepharoptosis is usually aponeurotic, due to stretching or disinsertion of the levator aponeurosis. Treatment is surgical and can be performed by three common procedures - Levator advancement, Müller's muscle-conjunctival resection procedure and White line advancement. A number of reports inspected the possibility that Blepharoptosis repair procedures may cause deterioration in dry eye status. The investigators would like to assess whether there is a difference between the different procedures in their influence on dry eye status.

Detailed Summary:
Sponsor: Rabin Medical Center

Current Primary Outcome: Diagnosis of objective or subjective deterioration in dry eye status [ Time Frame: 6 months ]

Dry eye status will be measured by a composite of tests, including Ocular surface disease index (OSDI) questionnaire (which indicates subjective status), and a number of objective tests - Shirmer test, Flurocein dye, Lissamine green dye and tear breakup time


Original Primary Outcome: Same as current

Current Secondary Outcome: Ptosis repair procedure success [ Time Frame: 6 months ]

Success will be assessed by comparison of margin reflex distance1 (MRD1) measurement before and after surgery


Original Secondary Outcome: Same as current

Information By: Rabin Medical Center

Dates:
Date Received: July 12, 2015
Date Started: July 2015
Date Completion:
Last Updated: July 15, 2015
Last Verified: July 2015